Athletic Bilbao coach Marcelo Bielsa said the impact Fernando Llorente has on the team's mood is just as important as his goalscoring ability.
Atletico are keen to register their third home victory when they take on Zaragoza, who will be hoping to avoid their third straight defeat.
Barcelona coach Pep Guardiola has insisted the club's success during his tenure is down to the presence of striker Lionel Messi in the squad.
Espanyol midfielder Raul Baena is not worried about spending time on the bench in the last three fixtures, as team success is more important.
Getafe are hoping to pick up points for the fourth straight game when they take on Valencia, who are looking for their fourth home victory.
Granada are desperate to avoid their third consecutive game when they take on Sevilla, who are looking to register their fifth home victory.
Juan Ignacio Martinez has warned Levante that Osasuna will be motivated to beat the league leaders, even though they are not Barca or Madrid.
Malaga midfielder Joaquin Sanchez has declared the team will continue to back coach Manuel Pellegrini to pull them out of the current slump.
Osasuna will be hoping to pick up points for the third consecutive game when they take on Levante, who have yet to lose a game this season.
Racing will be hoping to register their first win of the season when they face Betis, who are desperate to avoid their sixth straight defeat.
Rayo Vallecano manager Jose Ramon Sandoval is convinced their next opponents Villarreal are working well and that results will soon follow.
Real Betis coach Pepe Mel has drafted in Alex Martinez from the reserves as Nacho Perez is a doubt for their clash against Racing Santander.
Real Madrid midfielder Nuri Sahin will have to wait a little longer to make his full debut as Jose Mourinho wants him to be 100 per cent fit.
Real Mallorca will be hoping to avoid their second straight defeat when they face Barcelona, who are looking for their fifth home victory.
Real Sociedad will be hoping to avoid their second straight defeat when they face Real Madrid, who are looking for their fourth away victory.
Zaragoza will be hoping to avoid their third straight defeat when they take on Atletico, who have conceded only one goal at home this season.
Manager Marcelino has confirmed that Sevilla will be looking to sign a striker in January and that the player is eager to return to Spain.
Sporting Gijon are hoping to register their third consecutive win when they take on Bilbao, who will be keen to avoid their third away defeat.
Valencia coach Unai Emery insisted that his side are not thinking about Leverkusen as it will only make it harder for them to beat Getafe.
Villarreal will be desperate to avoid their third straight defeat when they take on Rayo, who are looking to register their third away win.