Athletic Bilbao star striker Fernando Llorente has been able to train without problems, but he is still a doubt for their clash against Getafe.
Atletico Madrid midfielder Koke believes this is the best time for his side to win away from home, now that they have a new coach on the bench.
Manchester Utd reportedly sent scout Martin Ferguson to watch Barcelona youngster Isaac Cuenca during their Copa del Rey clash against Osasuna.
Espanyol coach Mauricio Pochettino insists their Copa first leg defeat to Cordoba will not affect his team ahead of the clash against Barcelona.
Getafe are looking to register their third consecutive victory when they take on Athletic Bilbao, who have dropped 12 points away from home.
Granada are hoping to pick up points for the fourth time in five games when they take on Real Madrid, who have lost only one match at home.
Arouna Kone admits he is relieved by the fact that he is not involved in the African Nations Cup because Levante are his priority this year.
Malaga coach Manuel Pellegrini is set to reintroduce Weligton and Maresca into his squad for the clash against direct rival Atletico Madrid.
Coach Jose Luis Mendilibar has warned Osasuna to be wary of Sociedad, who are their direct rival 'in everyway', despite their league position.
Racing are determined to pick up points for the fourth straight game when they face Zaragoza, who are still looking for their first away win.
Rayo Vallecano are hoping to avoid their third consecutive defeat when they take on Sevilla, who are looking for their second away victory.
Real Betis are looking to register their third consecutive win when they take on Sporting Gijon, who are keen to avoid their fifth away defeat.
Real Madrid coach Jose Mourinho has made it clear that Kaka is still a part of his plans, despite speculation linking him to Paris St-Germain.
Mallorca are hoping to avoid their second consecutive defeat when they take on Levante, who have dropped only three points at home this season.
Real Sociedad are hoping to pick up points for the sixth consecutive game when they take on Osasuna, who are looking for their second away win.
Real Zaragoza are desperate to avoid their sixth consecutive defeat when they take on Racing, who are hoping to register their third home win.
Coach Marcelino said Sevilla deserved better in their first leg clash with Valencia as his team controlled the game even after falling behind.
Sporting Gijon are hoping to register their second win in five games when they take on Betis, who have dropped 11 points at home this season.
Valencia head coach Unai Emery was happy to see his team played a complete game against Sevilla, but admitted it was not a great performance.
Villarreal are desperate to avoid their fourth defeat in five games when they take on Valencia, who are looking for their fifth away victory.